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Best Papers in General Surgery
The five that matter, every day.
A study analyzing 937 patients undergoing pancreatoduodenectomy after biliary drainage revealed significant findings regarding endoscopic ultrasound-guided choledochoduodenostomy (EUS-CDS) versus conventional techniques. Major postoperative complications were lower in the EUS-CDS group (19%) compared to the ERCP group (33%). The overall complication rates were similar across methods.…
A real-world safety analysis of histotripsy in 230 liver tumor patients revealed a low complication rate of 5.2%, with the majority classified as minor. Complications greater than grade II were rare, occurring in just 1.3% of cases. This novel non-invasive ultrasound technology, approved by the…
After a decade of follow-up in the SM-BOSS trial, Roux-en-Y gastric bypass (RYGB) demonstrated superior efficacy in achieving percentage excess body mass index loss compared to sleeve gastrectomy (SG), with means of 65.9% and 56.1% respectively. Though total weight loss showed no significant difference, patients…
A comparative analysis of metabolic and bariatric surgery (MBS) versus glucagon-like peptide-1 receptor agonist (GLP-1 RA) therapy indicated that MBS significantly lowers the hazard of cardiovascular disease in patients with obesity. Specifically, MBS demonstrated a reduced risk for the primary composite outcome of cardiovascular disease…
Racial disparities in pancreatic cancer survival are linked to distinct immune microenvironments and genomic profiles. In a comprehensive analysis of 4,679 pancreatic adenocarcinoma samples, African American patients exhibited a higher frequency of TP53 mutations than European Americans. Additionally, gene expression profiling indicated significant immunologic differences…
A hybrid systematic review examined 92 papers on trauma triage tools (TTTs), revealing significant variability in the application of prehospital characteristics across international studies. While higher-level categories such as physiological measurements and injury mechanisms were consistent, the specific thresholds and interpretations used varied widely. This…
A systematic review and meta-analysis of 16 cohort studies demonstrated that patients undergoing pelvic peritoneal reconstruction (PPC) during abdominoperineal resection for rectal cancer experienced significantly lower rates of postoperative complications. The PPC group showed reduced odds for intestinal obstruction (OR = 0.22), surgical site infections…
First-intention endoscopic ultrasound-guided drainage (EUS-pcd) using lumen-apposing metal stents (LAMS) demonstrated a technical success rate of 97.0% and a clinical success rate of 95.2% in managing postoperative collections (PCs) from various surgeries. The median size of collections was 7.6 cm, occurring about 19 days post-surgery.…
A systematic review and meta-analysis of 12 studies involving 480 patients indicated that minimally invasive endoscopic onlay repair (endor) for diastasis recti and ventral hernia is a safe technique. The intraoperative complication and conversion rates were low at 1%, with a seroma rate of 25%.…
A multicentre, parallel-arm, randomised trial in China aims to assess whether continuous glucose monitoring (CGM) improves surgical outcomes for patients with diabetes or impaired glucose tolerance compared to conventional monitoring. The study targets a significant cohort of over 10,000 participants and measures the comprehensive complication…
