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Best Papers in General Surgery
The five that matter, every day.
Analysis of 1170 elective abdominal surgery patients revealed two acute pain trajectory clusters: high and low. Those in the high pain groups experienced almost double the likelihood of developing chronic postsurgical pain (cpsp), along with a significantly poorer recovery quality. Mediation analysis indicated that the…
A systematic review produced fourteen new consensus-based recommendations for prehospital bleeding control in patients with multiple and/or severe injuries. Analyzing fifteen studies on interventions such as tourniquets and pelvic binders, researchers highlighted the importance of bleeding control as a treatment objective. Despite the strong consensus…
Multiparametric MRI (mpmri) demonstrated superior diagnostic accuracy for restaging locally advanced gastric cancer after neoadjuvant therapy, with significant inter-reader agreement noted. The accuracy for T restaging reached 0.586 for mpmri, outperforming other imaging methods. Importantly, mpmri achieved an area under the curve of 0.879 for…
Indocyanine green fluorescence angiography (ICGFA) significantly lowers anastomotic leak rates during colorectal surgery. Analysis of 45 studies involving 14,333 patients revealed overall leak rates of 4.5% with ICGFA compared to 8.5% without it (OR: 0.47, p < 0.001). Notably, in rectal resections, leaks occurred at…
The study analyzed 973,520 cases of metabolic and bariatric surgery, revealing that conditions such as GERD, COPD, smoking, and specific surgical procedures significantly heighten the risk of inpatient postoperative care (IP-POC) needs. Male patients exhibited increased severity but lower likelihood of complications, while Black and…
A meta-analysis of ten randomized controlled trials demonstrated that Roux-en-Y gastric bypass (RYGB) significantly enhances outcomes for patients with type 2 diabetes mellitus (T2DM). Key findings revealed improved compliance rates, higher remission rates, and reductions in glycated hemoglobin (HbA1c) and fasting blood glucose levels. Additionally,…
A new radiomics model utilizing contrast-enhanced ultrasound (CEUS) shows promising results for preoperative prediction of neoplastic gallbladder polyps over 10 mm. Analyzed data from 119 patients produced a logistic regression model that demonstrated an AUC of 0.95 in internal validation. This model enhances diagnostic precision,…
A study involving 716 patients with colorectal liver metastases found that simultaneous curative resection significantly improves overall survival compared to palliative treatment. Curative resection emerged as an independent prognostic factor, with a hazard ratio of 1.95 indicating nearly double the survival benefit. The research also…
A machine-learning framework quantified the impact of clinical versus nonclinical influences on postoperative length of stay after colectomy. Analysis of 96,081 patients revealed that clinical factors accounted for only 29-54% of length of stay variability. Despite optimizing these variables, significant unexplained variance remained, indicating the…
Initial results from Finland's colorectal cancer screening program indicate a high yield with 63 cases of CRC detected, including 49% diagnosed at early stage I. Among 23,388 participants, a 64% return rate for fecal immunochemical tests (FIT) was observed, with 79% of positive results leading…
