Newsletter
Best Papers in General Surgery
The five that matter, every day.
A clinical trial aims to determine if a loading dose of cefoxitin followed by continuous infusion reduces surgical site infections (SSIs) in colorectal surgery compared to intermittent bolus administration. Conducted across multiple centers with 2000 patients, the study seeks to demonstrate that this alternative administration…
Over a decade, 52.7% of 14,237 adverse events in a South African surgical department were linked to human error. This resulted in an error rate of 14% per admission and 2% per inpatient day, correlating with increased length of hospital stays and mortality. Addressing these…
A single-center study evaluated 60 patients with chronic abdominal pain linked to the appendix, using cholangioscope-assisted endoscopic retrograde appendicitis therapy (ERAT). Findings revealed a 100% technical success rate and 90% clinical success. Post-procedure, 90% of patients reported an abdominal pain score of zero after an…
A systematic review and meta-analysis aims to assess the impact of racism on surgical outcomes in the USA and Canada. The study will compile data on adverse postoperative events for racialised versus non-racialised patients across common and high-risk surgeries. Key outcomes include mortality and complication…
A study involving 1,254 participants revealed that an automatic quality control system (AQCS) significantly improved adenoma detection rates during routine colonoscopy. The AQCS-assisted group achieved a detection rate of 32.7% compared to 22.6% in the standard group (relative risk 1.60, p
Advanced machine learning techniques, particularly the xgboost algorithm, have shown exceptional predictive accuracy for identifying the risk of postoperative gastroparesis in colon cancer patients after complete mesocolic excision. From a cohort of 1,097 patients, featuring 87 gastroparesis cases, xgboost achieved an area under the curve…
Combining radiofrequency ablation (RFA) with immunotherapy shows promising efficacy and manageable safety for hepatocellular carcinoma (HCC). It induces immunogenic substances and regulates immune cell responses, enhancing the anti-tumor immune effects and reconstructing the tumor microenvironment. This synergy reduces the risk of cancer recurrence and metastasis,…
Advances in endoscopic techniques for treating upper gastrointestinal submucosal tumors (SMTs) are promising, with innovations enhancing diagnosis and therapeutic options. The study evaluates diverse endoscopic strategies and their efficacy, indicating they are minimally invasive and expedite recovery compared to traditional surgery. Despite these advancements, concerns…
Higher levels of surgical team familiarity significantly reduce patient complications and adverse events, according to a cohort study of over 8,500 operations. Specifically, investigators found that initial collaborations cut composite adverse event rates from 23% to 16.5%. The related odds ratios indicated notable decreases in…
In a prospective study involving 587 colorectal cancer patients, non-enhanced abbreviated MRI (ne-amri) demonstrated superior diagnostic accuracy for liver metastases detection compared to contrast-enhanced CT (ce-ct). Across three surveillance rounds, ne-amri consistently showed higher lesion-based detection rates and better patient-based metrics, including sensitivity and specificity.…
