Newsletter
Best Papers in General Surgery
The five that matter, every day.
A meta-analysis revealed that sleeve gastrectomy (SG) significantly reduces the apnea-hypopnea index (AHI), body mass index (BMI), weight, and fat areas while enhancing forced vital capacity (FVC) and sleep metrics in patients with obesity and obstructive sleep apnea (OSA). Key post-surgical benefits included decreased arousal…
A novel machine learning model has been developed to predict gangrenous cholecystitis, utilizing clinical data from 1006 patients. Employing the XGBoost algorithm and SHAP for interpretability, key clinical features were identified, including white blood cell count and d-dimer levels. This explainable model aims to assist…
A systematic review and meta-analysis of seven randomized controlled trials, involving 731 patients, confirms that the Enhanced Recovery After Surgery (ERAS) protocol significantly shortens hospital stays by an average of 2.49 days compared to conventional care. Furthermore, it shows potential reductions in hospital costs, readmission…
A multi-institutional study identified key predictors for a "textbook outcome" in liver surgery for intrahepatic cholangiocarcinoma (ICC). The absence of post-hepatectomy liver failure, low intraoperative blood loss, no major infectious complications, and achieving R0 resection were linked to improved overall survival of at least 12…
A study developed predictive models to aid surgical decision-making for hepatic cystic echinococcosis (CE). Analyzing data from 406 patients, the Cox regression model achieved a concordance index of 0.94 and AUC of 0.96. The decision tree model highlighted imaging findings, cyst stage, and symptoms as…
Researchers developed three nomograms to predict short-term and long-term outcomes in patients with large hepatocellular carcinoma (HCC) post-liver resection. These models demonstrated good predictive performances with c-indices of 0.764 for surgical risk, 0.709 for overall survival (OS), and 0.695 for recurrence-free survival (RFS) in validation…
A systematic review and meta-analysis of 11 randomized controlled trials revealed that combining enteral and parenteral nutrition significantly improves postoperative recovery, nutritional function, and immune responses in patients with gastrointestinal cancer. The findings suggest that this combined approach offers superior energy intake and prognosis compared…
Research reveals that while minimally invasive surgery (MIS), especially robotic surgery, offers significant benefits, safety-net hospitals often lack the necessary resources. This results in reduced access for underserved and marginalized populations to essential surgical interventions. Consequently, patients in these communities miss out on improved outcomes,…
A machine learning model using extreme gradient boosting (XGBoost) was developed to predict bile leaks after hepatectomy for liver cancer. The model analyzed data from over 22,000 patients, achieving areas under receiver operating characteristic curves (AUROC) of 0.748, 0.719, and 0.711 in various patient cohorts.…
The implementation of the Emergency Laparotomy Audit (EMLA) perioperative care bundle resulted in notable improvements in patient outcomes for emergency laparotomy procedures. Surgical complications decreased from 34.8% to 20.6%. The study encompassed a cohort of 429 patients, divided into pre- and post-intervention groups, assessing length…
