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Best Papers in General Surgery
The five that matter, every day.
A study on robot-assisted minimally invasive McKeown esophagectomy revealed a significant reduction in operation time associated with increased surgical proficiency. Analyzing 83 cases, researchers found that transitioning from the initial learning phase (cases 1-27) to the proficiency phase (cases 28-83) resulted in a drop in…
The study demonstrated that triplet induction chemotherapy with folfirinox results in an objective response rate of 80% and a disease control rate of 92% in patients with synchronous metastatic rectal cancer (smrc). Analysis of 146 patients revealed that 69% of those with resectable metastases underwent…
A multicentric study demonstrated the safety and efficacy of liver venous deprivation (LVD) in enhancing future liver remnant (FLR) volume prior to major hepatectomy. Out of 192 patients, LVD achieved a 100% technical success rate, with only a 2.6% rate of severe complications. FLR volume…
A recent systematic review and meta-analysis examined alternative colorectal anastomotic devices, finding a pooled complication rate of 9.7% in human studies. Notably, the leak rate for compression anastomoses was only 3.3%, demonstrating no variation among studies. This review included 18 studies with a total of…
Findings indicate that using mesh bridging for temporary closure of burst abdomen significantly reduces hospital stays and severe complications compared to negative pressure wound therapy (NPWT). Among 119 patients studied, those receiving mesh bridging had a remarkable average stay of 29 days, opposed to 93…
A systematic review of 267 clinical practice guidelines revealed significant variability in perioperative patient safety recommendations. Among 4,666 recommendations identified, 44.9% were strongly endorsed; however, only 18 guidelines excelled in methodological quality. A notable gap was found in recommendations related to pre-admission and post-discharge care.…
A population-based analysis of 3,694 gastric cancer patients with liver metastases revealed that those undergoing cancer-directed surgery experienced significantly longer median overall survival, 12 months versus 6 months for non-resection patients. After adjusting for selection bias, Cox regression indicated a substantial survival benefit, with a…
In an international multicenter study, early recurrence in resected intraductal papillary mucinous neoplasm (IPMN)-derived pancreatic cancer was identified at 10.5 months. Among 381 patients, 42% experienced recurrence, with 38% classified as early recurrences. Key predictors included CA19-9 levels and N2 disease staging. The study stratified…
In patients with intermediate-stage hepatocellular carcinoma (HKLC stage IIB), preoperative transarterial chemoembolization (TACE) significantly improves survival outcomes compared to upfront surgery alone. A study involving 154 matched patients found that the median overall survival for the TACE group undergoing surgical resection was 90.97 months, versus…
An innovative decision tree algorithm was developed to classify patients with acute cholecystitis based solely on laboratory parameters. Analyzing 1,352 cases, the algorithm showed an impressive 82.17% accuracy in predicting the need for surgery and 73.86% accuracy for identifying gangrenous cholecystitis. Key parameters included the…
