Newsletter
Best Papers in General Surgery
The five that matter, every day.
An innovative AI-based recognition model for detecting colorectal liver metastases during contrast-enhanced intraoperative ultrasonography was developed. By integrating the basic recognition model and a subtraction model, a combination model demonstrated superior accuracy, reaching 96.5%. Overall, the combination model achieved an exceptional area under the curve…
A systematic review evaluated 1,417 patients undergoing liver resections with either ultrasonic devices or clamp-crushing techniques. While the clamp-crush method yielded shorter operation times, the ultrasonic group demonstrated significantly less blood loss and lower transfusion rates. Both groups had comparable mortality and postoperative bleeding rates;…
A complex parenchyma-sparing hepatectomy was successfully performed on a 61-year-old woman with multiple bilobar colorectal liver metastases after she showed a partial response to second-line chemotherapy. Utilizing advanced three-dimensional reconstruction and intraoperative ultrasound for guidance, clinicians executed a unique transection of several liver segments, significantly…
Peptide receptor radionuclide therapy (PRRT) significantly improves progression-free survival (PFS) and overall survival (OS) in patients with advanced gastroenteropancreatic neuroendocrine tumors (GEP-NETs) who progress after surgical resection. Among 237 analyzed patients, those receiving PRRT experienced a median PFS of 32.4 months compared to 11.0 months…
Laparoscopic fundoplication significantly improves esophageal motility in patients with gastroesophageal reflux disease (GERD), irrespective of their initial motility status. A study involving 124 patients found that successful fundoplication was associated with normalization of motility, with 103 achieving good outcomes. All procedures were performed laparoscopically without…
A screening program for high-grade anal dysplasia has been successfully implemented at a Brazilian cancer center. Over 324 exams were conducted between March 2022 and June 2024, revealing anal high-grade squamous intraepithelial lesions (AHSIL) in 38.2% of high-risk patients. Specifically, AHSIL was detected in 34.9%…
A new surgical technique for subtotal esophagectomy effectively reduced anastomotic leakage (AL) rates. Researchers compared outcomes between a conventional group and a modified procedure group. AL decreased from 16.9% to 2.8% (p=0.002), with further analysis showing 14% in the conventional group versus 0% in the…
An expert panel from the Japan Liver Cancer Association and Japanese Society of Hepato-Biliary-Pancreatic Surgery has established clear criteria for assessing the oncological resectability of hepatocellular carcinoma (HCC). Three classifications were introduced—resectable, borderline resectable 1, and borderline resectable 2—distinguishing treatment strategies and anticipated survival outcomes.…
Stool-based surveillance for individuals with post-polypectomy indications has been shown to safely decrease the need for colonoscopies by 15% to 41%. A study of 3,453 participants found that multitarget stool DNA tests were most effective (AUC 0.72), but also more costly than colonoscopy. In contrast,…
In a study involving 1,558 pancreatic cancer patients, 13.9% exhibited normal carbohydrate antigen 19-9 (ca19-9) levels, linked to significantly longer median survival rates (18.1 vs. 9.7 months). Those with stage IV ca19-9-normal cancer had a 5-year survival chance of 22.4%, compared to 6.8% in the…
