Newsletter
Best Papers in General Surgery
The five that matter, every day.
A new machine learning model successfully predicted early extrahepatic recurrence (EEHR) following curative resection of colorectal liver metastases (CRLM). Among 1,410 patients, 131 (9.3%) experienced EEHR, with median overall survival significantly lower for affected patients (35.4 months) versus those without (120.5 months, p < 0.001).…
Laparoscopic splenectomy plus esophagogastric devascularization significantly reduced hepatic venous pressure gradient (HVPG) in patients with portal hypertension, with 66% showing a decrease. Notably, those exhibiting a postoperative HVPG reduction greater than 20% demonstrated improved recurrent hemorrhage-free survival rates compared to others. Baseline HVPG and preoperative…
A new model integrating radiomics, pancreatic duct diameter, and body composition analysis effectively predicts clinically relevant postoperative pancreatic fistula in patients undergoing pancreaticoduodenectomy. This combined approach achieved an area under the ROC curve of 0.839, outperforming existing models. Internal validation through 1,000 bootstrap resamples demonstrated…
A novel tool, SICNESS, has been developed to identify and categorize non-technical errors linked to surgical mortality. Validated through a two-pilot approach using 844 mortality cases from Australia and New Zealand, the tool demonstrated high inter-rater reliability, particularly in leadership and decision-making aspects. Its systematic…
The study compared intraoperative (IS) and preoperative (PS) indocyanine green administration for near-infrared cholangiography during laparoscopic cholecystectomy. While both methods yielded similar signal-to-background ratios, IS significantly lowered liver fluorescence intensity and achieved higher visualization scores for common hepatic ducts. Furthermore, IS facilitated a quicker critical…
A new predictive model, combining small ribonucleic acids (srnas) and clinical factors, shows promise in forecasting pathologic complete response (pcr) in esophageal squamous cell carcinoma post-neoadjuvant chemoradiotherapy. Among 99 patients, significant predictors included isomirs of let-7b and mir-93, plus specific clinical indicators. The model achieved…
In a systematic review of 63,523 pregnant women, laparoscopic cholecystectomy (LC) emerged as the most favorable treatment for gallbladder disease. It significantly reduced risks of preterm delivery (RR: 0.23), fetal complications (RR: 0.42), and maternal complications (RR: 0.44) compared to open cholecystectomy. While cholecystectomy is…
A novel nomogram has been developed to predict postoperative biliary fistula (PBF) risk after pancreaticoduodenectomy. Analyzing data from 196 patients, researchers identified diabetes, low albumin, postoperative gastroparesis, abdominal bleeding, abdominal infection, and pancreatic fistula as independent risk factors. The model demonstrated good discriminative ability with…
A significant majority (77%) of older cancer patients opted for telemedicine consultations over in-person visits at the Cancer and Aging Interdisciplinary Team clinic. Factors influencing in-person visit choices included older age, lower educational status, living in New York City, cognitive impairments, performance measure challenges, and…
A novel nomogram crafted to forecast severe postoperative complications in elective hepato-pancreato-biliary surgery following COVID-19 breakthrough infections demonstrated high accuracy. The model utilized data from 2,636 patients and identified significant predictors, including timing of surgery relative to the infection and vaccination status. With an area…
