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General Surgery

Best Papers in General Surgery

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Surg Endosc3 Oct 2024

Endoscopic sleeve gastroplasty shows comparable outcomes to surgery

A retrospective analysis of patients undergoing endoscopic sleeve gastroplasty (ESG) versus laparoscopic sleeve gastrectomy (LSG) revealed similar improvements in obesity-related comorbidities. While LSG resulted in greater percentage total body weight loss at 6 months, 1 year, and 2 years, ESG was associated with shorter hospital…

Obes Surg3 Oct 2024

Machine learning models outperform traditional risk scores in bariatric surgery

Advanced machine learning techniques, particularly random forest, demonstrated superior performance in predicting 30-day complications in metabolic bariatric surgery compared to the established MBSAQIP risk score. The random forest model achieved an area under the receiver operating characteristic curve (AUROC) of 0.94 in training and 0.88…

Tech Coloproctol3 Oct 2024

Enhanced recovery protocols significantly reduce delayed recovery rates

Identifying key factors impacting recovery, clinicians analyzed data from 1,535 patients undergoing elective colorectal surgery across 22 hospitals. Despite a median adherence to protocols at 75%, 31.7% experienced delayed recovery. The study highlighted six critical protocol items, including pre-admission counseling and early removal of the…

Endosc Ultrasound3 Oct 2024

EUS-guided biopsy yields valuable mutation data in pancreatic cancer

A study evaluated the feasibility of EUS-guided fine-needle biopsy (EUS-FNB) for next-generation sequencing (NGS) in unresectable pancreatic ductal adenocarcinoma (PDAC). The technical yield of EUS-FNB met criteria in 48% of cases, while the molecular yield was remarkably high at 98%. This means that nearly all…

Ann Surg Open2 Oct 2024

Racial Disparities Impact Surgical Outcomes in Diverse Patient Populations

A comprehensive analysis of over 7.5 million surgical patients reveals significant racial disparities in postoperative outcomes. White, Asian, and Native Hawaiian patients exhibited better outcomes compared to Black and American Indian patients, who faced higher rates of complications. Additionally, socio-economic factors such as wealth, healthcare…

J Clin Gastroenterol2 Oct 2024

EUS-BD offers reduced pancreatitis risk compared to ERCP

A systematic review and meta-analysis revealed that endoscopic ultrasound-guided biliary drainage (EUS-BD) is a safe alternative to ERCP transpapillary drainage (ERCP-TPD) for primary biliary drainage in patients with distal malignant biliary obstruction (DMBO). Among 815 patients analyzed, clinical and technical success rates were similar for…

Int J Colorectal Dis2 Oct 2024

Biological agents significantly reduce surgery rates in Crohn’s disease

In the era of biological agents, Crohn's disease patients show varying surgery rates based on Montreal classifications. Notably, type B3 patients have the highest likelihood of requiring surgery, while type A1 patients tend to undergo surgery earlier than A2 and A3. The use of biological…

Int J Surg2 Oct 2024

Radiation-emitting stents improve survival in cholangiocarcinoma patients

In a multicenter trial, the use of radiation-emitting metallic stents (REMS) combined with hepatic arterial infusion chemotherapy (HAIC) significantly enhanced overall survival (10.2 months vs. 6.7 months) and time to symptomatic progression (8.6 months vs. 5.4 months) compared to self-expandable metallic stents (SEMS) with HAIC…

J Hepatobiliary Pancreat Sci2 Oct 2024

Liver immune status index enhances prognostic accuracy in HCC

The liver immune status index (LISI) demonstrated strong predictive capabilities for postoperative outcomes in hepatocellular carcinoma (HCC) patients, particularly with vascular invasion. In a study of 1,337 hepatectomies, LISI effectively stratified patients into distinct risk groups, correlating significantly with established prognostic markers. Notably, LISI provided…

Ann Surg Open1 Oct 2024

Intraoperative factors improve prediction of hospital stay length

A new model predicting length of stay (LOS) after colorectal surgery demonstrates enhanced accuracy by including intraoperative risk factors. The intraoperative prediction model (IP model) achieved an area under the curve (AUC) of 0.84, outperforming the preoperative model (PP model) with an AUC of 0.75.…