Study of 118 patients with malignant peritoneal mesothelioma revealed cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC) led to longer overall and progression-free survival. The platinum-pemetrexed combination was effective for metastatic patients and those medically inoperable. Non-surgical patients had poorer prognoses. CRS-HIPEC emerged as a safe and effective treatment, offering better survival outcomes and […]
Category: General Surgery
Superior outcomes of laparoscopic liver resection for NAFLD-associated HCC
Comparing laparoscopic liver resection (LLR) and open liver resection (OLR) for nonalcoholic fatty liver disease-associated hepatocellular carcinoma (NAFLD-HCC), LLR showed lower rates of complications, blood loss, transfusion, and shorter postoperative stay. Both groups had comparable major morbidities and survival outcomes. LLR appears to be a preferred treatment option over OLR for NAFLD-HCC, pending careful patient […]
Nomogram Predicts MSA Explantation Risk
Study developed a nomogram to predict magnetic sphincter augmentation (MSA) explantation, using variables like preoperative demeester score, GERD quality of life score, manometry values, and BMI. The scoring tool helps in preoperative patient selection and treatment decisions, aiding in determining the probability of explantation before MSA implantation, with potential benefits for clinical practice. Journal Article […]
Ultrasound Predicts Lymphatic Spread in Papillary Thyroid Cancer
Ultrasound features like loss of fatty hilum, architectural distortion, enlarged size, and microcalcifications are associated with metastatic papillary thyroid cancer. A combination of these features shows high specificity and positive predictive value for malignancy. This study suggests a risk stratification model based on these ultrasound characteristics could improve the classification of nodal metastases in patients […]
Sarcopenia Linked to Worse Outcomes in Pancreatic Surgery
High prevalence of sarcopenia and sarcopenic obesity in elderly male patients undergoing pancreatic surgery was associated with increased risk of severe postoperative complications. Visceral obesity and malnutrition did not impact outcomes significantly. Perineural invasion was common but unrelated to body composition. Findings highlight the need for preoperative evaluation of skeletal muscle and tailored interventions to […]
OAGB and RYGB Improve Renal Function Equally
One-anastomosis gastric bypass (OAGB) and Roux-en-Y gastric bypass (RYGB) showed similar improvements in renal function one year post-surgery, with OAGB leading to greater weight loss. Both procedures resulted in significantly higher estimated glomerular filtration rates. Younger age and lower baseline renal function were associated with better postoperative outcomes. OAGB could be a viable option for […]
Robotic CME Effective for Right Colon Cancer
Feasibility and efficacy of robotic complete mesocolic excision (CME) with intracorporeal anastomosis for right colon cancer were analyzed in 110 patients. Results show a median operative time of 184 minutes, minimal blood loss, and low complication rates. Conversions were minimal, with acceptable postoperative outcomes. Robotic CME with central vessels ligation appears safe and effective for […]
Reevaluating EMS Impact Assessment in LMICs
Emergency medical services impact evaluations in low and middle-income countries must prioritize community-led approaches, moving beyond mortality outcomes to consider factors like response times, economic impacts, and inclusion of underprivileged minorities. By co-creating context-tailored measures of success with local stakeholders, a decolonial holistic approach can shift focus towards long-term wellbeing and sustainability, challenging neocolonial hegemony […]
FGFR2 Alterations Enhance Survival in iCCA Patients
Meta-analysis reveals patients with intrahepatic cholangiocarcinoma (iCCA) and FGFR2 alterations have significantly better overall survival outcomes compared to those without. Results suggest FGFR2 alterations could serve as a promising therapeutic target for managing iCCA, especially in cases of metastatic or unresectable tumors. This study presents innovative insights into targeted therapy for iCCA, highlighting the potential […]
Improved Outcomes with Splenic Artery Embolization in High-Grade Splenic Injuries
Splenic artery embolization (SAE) demonstrates a 72% reduction in in-hospital mortality, shorter ICU length of stay, and lower transfusion requirements compared to splenectomy for hemodynamically stable adult trauma patients with high-grade blunt splenic injuries (Grade ≥ IV). SAE is associated with significantly improved outcomes, making it a potentially safer and more effective management approach for […]