Category: General Surgery

Quality of Life Thresholds in Crohn’s Disease

Study establishes quality of life thresholds using SIBDQ scores in Crohn’s disease patients, identifying a ‘resection red zone’ indicating surgery discussion need. Results show a worse SIBDQ score increases odds of bowel resection. SIBDQ enhances predictive value for surgery beyond clinical factors. Patient-reported outcomes aid in surgical decision-making, highlighting personalized burden understanding and potential benefits […]

Genetic Background Influence on Weight Loss After Bariatric Surgery

Individuals with lower polygenic risk scores experienced better weight loss outcomes after bariatric surgery compared to those with higher scores, especially in patients undergoing roux-en-y gastric bypass. Genetic background, assessed through polygenic risk scores, plays a significant role in long-term weight loss post-surgery, alongside factors like sex, age, and initial BMI. These findings suggest the […]

Improved Survival with CRS + HIPEC in HCC-PM Patients

CRS + HIPEC provides significant benefits to HCC-PM patients, with 89.0% 1-year and 3-year OS rates. Some patients achieved prolonged PFS, enhancing treatment options for this challenging condition. Incorporating CRS + HIPEC into the treatment regimen is a strategic therapeutic choice for HCC-PM patients, supported by the study’s findings of extended survival outcomes. Journal Article […]

Predicting Biliary Complications in Liver Transplant Patients

Utilizing LASSO logistic regression, researchers identified key risk factors for biliary complications in end-stage hepatic alveolar echinococcosis patients post ex vivo liver resection and autotransplantation. A prognostic nomogram model incorporating age, bile duct dilation, portal hypertension, and resection segments showed good discrimination and accuracy. The model predicted biliary complications with an AUC of 0.818 and […]

Comparison of Malnutrition Screening Tools in Hospitalized Patients

Prompt identification of malnutrition among hospitalized patients is crucial. A study compared 5 screening tools based on GLIM criteria on 1,397 inpatients. Results showed GMS had highest sensitivity (87.40%) and NRS-2002, highest specificity (91.70%). MST aligned well with GLIM, emphasizing early diagnosis importance. Effective screening tools can improve treatment efficacy. Journal Article by Arslan S, […]

Preoperative ICG-R15 Testing Predicts Post-hepatectomy Liver Failure

Preoperative ICG-R15 testing effectively predicts post-hepatectomy liver failure (PHLF) following major liver resection. A retrospective review of 72 patients revealed that 38.9% experienced PHLF, with 33.3% being severity score B and 4.16% score C. Univariate and multivariate analyses identified future liver remnant, ICG-R15 levels, and blood transfusion as independent predictors of PHLF. These findings emphasize […]

Pathologic Complete Response and Survival Paradox in Locally Advanced Rectal Cancer

Pathologic complete response (PCR) after preoperative chemoradiation correlates with improved overall survival for locally advanced rectal cancer patients. While total neoadjuvant therapy (TNT) increases PCR rates, it does not improve overall survival. Patients achieving PCR after TNT have worse survival compared to those with chemoradiation alone. The route to achieving PCR may be a crucial […]

Impact of Fat Embolism on Trauma Patients

Study reveals fat embolism in trauma patients associated with higher mortality, complications, and costs. Fat embolism linked to younger age, higher healthcare resource utilization. Trends show rising mortality and hospitalization costs over time in fat embolism group. Early identification crucial to improve outcomes and resource allocation for trauma patients. Journal Article by Ali K, Cho […]

Sleeve Gastrectomy Promotes Type 2 Diabetes Remission

Significant weight loss and remission of type 2 diabetes mellitus were observed in patients post-sleeve gastrectomy. Patients exhibited low citrulline and high I-FABP levels preoperatively, which normalized postoperatively. The study found a positive correlation between the I-FABP/citrulline ratio and weight, BMI, glucose, insulin, and c-peptide levels. Sleeve gastrectomy not only improves enteroendocrine function but also […]

Intraoperative Hemodynamic Monitoring for Pancreatectomy

Advanced intraoperative hemodynamic monitoring combined with a clinical decision-making algorithm improved hemodynamic parameters during pancreatectomy, showing a 33.3% reduction in intraoperative hypotension, 31.6% increase in cardiac index, and 37.6% increase in stroke volume variation. Further investigation in larger studies is warranted to validate these findings. Journal Article by Galouzis N, Khawam M (…) Dull RO […]