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Best Papers in General Surgery
The five that matter, every day.
Researchers developed and validated machine learning-based predictive models for lymph node metastasis (LNM) in intrahepatic cholangiocarcinoma (ICC) using clinicopathological data from 345 patients. The study used six machine learning algorithms, identifying the Extreme Gradient Boosting (XGB) model as the best, with an average area under…
A multicenter retrospective study evaluated the benefits of repeating esophagogastroduodenoscopy (EGD) at specialized esophagogastric cancer (EGC) centers in Denmark before gastric and esophageal cancer surgery. Among 953 patients who underwent both initial EGD and EGD at referral to a specialized center, 644 cases (68%) lacked…
A prospective study combines ultrasound with the Modified Alvarado Score (MAS) for acute appendicitis diagnosis. Among 55 patients undergoing appendectomy, the combined MAS demonstrated high sensitivity (98.18%) and accuracy (89.09%), outperforming MAS and ultrasound alone. This approach, requiring no additional financial burden, presents a promising…
A systematic review and meta-analysis examined postoperative mortality in Ethiopia, revealing a pooled mortality rate of 4.53% (95% CI: 3.70-5.37). Significant factors associated with increased mortality included an American Society of Anesthesiologists score of ≥III (AOR: 2.45, 95% CI: 2.02-2.96), age ≥65 years (AOR: 3.03,…
Artificial intelligence models demonstrated high accuracy levels in predicting lymph node metastasis in early-stage colorectal cancers, outperforming traditional clinical guidelines. With models such as support vector machine and deep learning, there is potential for refining clinical decisions and improving outcomes in this critical area of…
In this open-label randomized trial, researchers assessed the efficacy of micronized purified flavonoid fraction in reducing posthemorrhoidectomy complications. Fifty patients who underwent hemorrhoidectomy were divided into two groups: a control group receiving standard care and a study group receiving standard care plus micronized purified flavonoid…
Study demonstrates that combining surgery with HIPEC significantly improves 5- and 10-year overall survival rates and relapse-free survival of LAMN perforation patients without impacting short-term outcomes. Analysis of 91 patients revealed higher survival rates in the HIPEC group compared to non-HIPEC group, highlighting the potential…
Fluorodeoxyglucose positron emission tomography (FDG-PET) effectively predicts lymph node status and prognosis in patients with esophageal squamous cell carcinoma (ESCC) undergoing esophagectomy after neoadjuvant chemotherapy (NCT). Researchers reviewed data from 124 ESCC patients and found that FDG-PET pre- and post-NCT correlated significantly with pathological lymph…
Modified mesohepatectomy offers a safe and beneficial alternative to trisectionectomy for treating bilobar congenital biliary dilatation. It results in higher residual liver volume, lower parenchyma resection rate, reduced complications, and optimal long-term outcomes, making it a valuable option for patients ineligible for major hepatectomy or…
Standardizing process in acute biliary disease, researchers identified modifiable factors impacting patients' time to theater, intraoperative time, and time to discharge. Implementing a perioperative management protocol based on imaging selection, operative grade identification, and drain placement could lead to significant cost savings and improved patient…
