Study identifies variations in lymph node metastases among different non-pancreatic periampullary cancer subtypes. Pancreatobiliary-type ampullary adenocarcinoma had higher lymph node metastasis rates. Distinct patterns of metastases were observed, with certain lymph node stations more frequently affected in different cancer types. Research highlights the need for standardized lymphadenectomy and pathology assessment for improved management of these […]
Category: General Surgery
Increased Long-Term Risk of Cancer in Patients with Diverticular Disease
Study findings show elevated relative risk of cancer, excluding colorectal, following diverticular disease diagnosis. There is a higher risk for lung, bronchi, trachea, and kidney cancers. The decreased risk of colorectal cancer may be due to colonoscopy with polypectomy in diverticular disease patients. Prevalence of cancer risk factors in diverticular disease patients likely contributes to […]
Frailty and TG/PG Increase Risk of Postoperative Pneumonia in Gastric Cancer Patients
Frailty and total or proximal gastrectomy (TG/PG) were found to be independent risk factors for postoperative pneumonia (POP) in patients with gastric cancer undergoing gastrectomy. A simple risk assessment method combining these factors effectively predicted and prepared patients for POP, with a 5.5% incidence rate and an area under the receiver operating characteristic curve of […]
Validation of Textbook Outcome Parameter in Esophageal Cancer Surgery
This study validates textbook outcome (TO) as a quality performance indicator (QPI) for esophageal cancer surgery. Postoperative complications, including Clavien-Dindo grade ≥3 complications, and 30-day readmission rate are associated with reduced survival. Updating TO parameters to include severe complications strengthens its association with increased survival, suggesting the need for a more precise QPI definition in […]
Minor impact of anastomotic leakage on long-term male urinary and sexual function
Anastomotic leakage after anterior resection for rectal cancer has a minor negative impact on male urinary function, leading to increased urinary incontinence rates. However, it does not significantly affect sexual function or increase risks of urinary frequency, permanent urinary catheter use, or sexual inactivity in the long term. Journal Article by Rutegård M, Jutesten H […]
Link Between Appendicitis and Diverticular Disease
A significant association was found between appendicitis and subsequent diverticular disease in a large German cohort study. Men had a stronger risk compared to women, with a higher 10-year incidence of diverticular disease in those with appendicitis. The findings emphasize the need for further research on the relationship and potential therapeutic interventions, such as probiotics, […]
Deep Learning System Outperforms Surgeons in Identifying Peritoneal Surface Metastases
Development and testing of a prototype deep learning surgical guidance system showed improved performance in identifying peritoneal surface metastases compared to oncologic surgeons. The system demonstrated potential for increasing identification of metastases by 5% and reducing unnecessary biopsies by 28% in a simulated clinical environment. Journal Article by Schnelldorfer T, Castro J, Goldar-Najafi A and […]
Autofluorescence-guided Hemithyroidectomy Enhances Parathyroid Gland Identification
Autofluorescence significantly improved parathyroid gland identification in hemithyroidectomy, boosting surgical confidence. The near-infrared camera enabled better visualization pre-procedure, leading to higher parathyroid identification rates compared to conventional surgery. This approach may benefit low-volume institutions without parathyroid surgery experience. Journal Article by Abood A, Rolighed L (…) Triponez F et 3 al. in Br J Surg […]
Tissue Sources for Pancreatic Cancer Organoids
Establishing patient-derived tumor organoids (PDTOs) from endoscopic ultrasound-guided biopsies yields success rates comparable to surgical specimens, offering viable options for personalized medicine in pancreatic cancer. In a meta-analysis of 24 studies, overall success rate was 63%. Pooled success rates for PDTO establishment from endoscopic ultrasound-guided biopsies, percutaneous biopsies, and surgical specimens were 60%, 36%, and […]
Body Composition Analysis as Frailty Biomarker in Abdominal Surgery
Prior studies found low skeletal muscle mass on CT scans linked to postoperative complications. This retrospective study analyzed body composition from CT scans to predict frailty and adverse outcomes after abdominal surgery. Results showed that higher muscle quantity and quality scores correlated with reduced risk of readmission, mortality, and morbidity, suggesting CT analysis offers an […]