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Best Papers in General Surgery
The five that matter, every day.
Laparoscopic radical antegrade modular pancreatosplenectomy (RAMPS) showed significantly higher rates of R0 resection (91.7% vs. 69.2%) and similar intraoperative blood loss and operative time compared to laparoscopic distal pancreatectomy with splenectomy. Both procedures had similar perioperative complication rates. The study demonstrates that laparoscopic RAMPS is…
Pancreatic ductal adenocarcinoma patients exhibit varied responses to therapy, with molecular subtyping revealing classical and basal-like subtypes, the latter associated with poorer outcomes. Two main tumor subtypes were identified, along with high-risk stromal subtypes linked to worse survival. Superior survival was seen with classical subtype.…
Unplanned conversion during laparoscopic liver resection for hepatocellular carcinoma is associated with higher blood loss, transfusion rate, hospital stay, and postoperative complications. However, the 5-year overall survival rate was similar in patients who underwent unplanned conversion and those who underwent laparoscopic liver resection.
Latino colon cancer patients in California face disparities, with lower rates of surgical resection, delays, and reduced receipt of recommended care compared to non-Latino White counterparts. Access to high-volume hospitals is linked to improved outcomes for Latino patients, emphasizing the importance of directing at-risk individuals…
Virtual informed consent, adopted during the COVID-19 pandemic, persists despite its resolution, challenging the traditional "information-transfer" model. This study argues for a "trust-building" model, emphasizing the interpersonal and systemic aspects of consent. It explores the limitations of virtual formats in fulfilling this comprehensive understanding and…
Sizing protocol (pop+2 vs pop+3) in magnetic sphincter augmentation did not impact outcomes like dysphagia, ph normalization, or need for dilation or removal. Upsizing did benefit patients with poor peristalsis or hypercontractile esophagus. Device size increase correlated with demographic and preoperative characteristics, suggesting it is…
Recent studies have confirmed the long-term safety and efficacy of laparoscopic distal gastrectomy compared to open gastrectomy for locally advanced gastric cancer. Ongoing trials are evaluating perioperative immunotherapy for resectable gastric cancers. Key trials like dante, gercor neonipiga, keynote-859, and spotlight are exploring targeted therapies…
A clinical model was developed to predict postsurgical intra-abdominal infection in blunt abdominal trauma patients based on a retrospective analysis of 553 patients from 7 medical centers. Independent risk factors were identified, including age, prehospital time, c-reactive protein, injury severity score, operation duration, intestinal injury,…
Restorative proctocolectomy with ileal pouch-anal anastomosis for ulcerative colitis improves quality of life but may not fully resolve extraintestinal disorders like primary sclerosing cholangitis, joint, skin, and eye issues. Treatment of pouchitis does not impact primary sclerosing cholangitis, but biologic therapies for pouch inflammatory disorders…
Simulation of 20,000 obese patients with non-alcoholic steatohepatitis found that sleeve gastrectomy (SG) led to a gain of 14.3 years compared to medical weight management (MWM), with only 5% of SG patients requiring liver transplantation (LT) after one year, compared to 9% in the MWM…
