Researchers investigated the feasibility of single-port sleeve gastrectomy (SPSG) by introducing a routine gastric suspension technique. Analyzing 171 patients, they compared SPSG to multiple-port sleeve gastrectomy (MPSG) and found no significant differences in preoperative and perioperative parameters, complications, or total weight loss percentages. SPSG demonstrated feasibility and non-inferiority compared to MPSG, suggesting its potential as […]
Category: General Surgery
Standardization and Trends in Lymphadenectomy During Laparoscopic Right Hemicolectomy in Italy
Italian researchers conducted a national study involving 788 patients from 76 highly specialized colorectal surgery wards to analyze the approach to lymphadenectomy during laparoscopic right hemicolectomy (RH). The study reveals that while laparoscopic RH is the preferred surgical technique, there is no standardized approach to lymphadenectomy. The analysis highlights the stable trend in surgical techniques […]
Effect of Bariatric Surgery on NAFLD/NASH: Improvement in Short-Term and Long-Term Outcomes
The prevalence of non-alcoholic fatty liver disease (NAFLD) is high in patients with obesity scheduled for bariatric surgery. This single-centre observational prospective cohort study aims to evaluate the impact of bariatric surgery on NAFLD/NASH. Initial findings show that bariatric surgery significantly improves NAFLD/NASH in the short term. However, the extent of this improvement and long-term […]
Economic burden of unmet surgical needs in Liberia
The economic burden associated with unmet surgical needs in Liberia was investigated through a nationwide enumeration of surgical procedures and providers. Researchers estimated that surgical activities prevented an economic loss ranging from $35 to $141 million in 2018, averting a total of 55,890 disability-adjusted life years (DALYs). Non-specialist physicians played a significant role in generating […]
Downstaging After Preoperative Chemoradiation Improves Survival in Locally Advanced Rectal Cancer
Patients with locally advanced rectal cancer who experience significant downstaging after preoperative chemoradiation have better overall survival compared to those with true pathologic stage 0-1 disease treated with upfront surgery. This was determined through a retrospective review of the national cancer database, which included a study population of 59,884 patients. The findings suggest that response […]
High-grade Solid Pseudopapillary Neoplasms of the Pancreas Have Distinct Clinicopathological and Genetic Features
A study comparing high-grade solid pseudopapillary neoplasms (hg-SPNs) with conventional SPNs (c-SPNs) found that hg-SPNs exhibit more aggressive malignant characteristics, such as larger tumor size, true necrosis, high-grade nuclear atypia, and lymphatic and/or venous invasion. All hg-SPN patients died of the disease, while c-SPN patients were alive without recurrence. Genetic analysis showed ctnnb1 mutations in […]
Molecular profiling improves overall survival in patients with intrahepatic cholangiocarcinoma
In a comprehensive multidisciplinary clinic, molecular profiling of intrahepatic cholangiocarcinoma (ICC) identified actionable molecular alterations in 45% of patients, including mutations and amplifications. Among 120 patients with molecular profiling, the detection of these alterations significantly improved mean overall survival (OS) by 10.5 months. Additionally, in 70 patients with non-metastatic ICC, the detection of actionable molecular […]
Using Circulating Tumor DNA as a Biomarker for Early Cancer Recurrence after Surgery
Researchers conducted a systematic review on the feasibility of using circulating tumor DNA (ctDNA) as a biomarker in the immediate postoperative period. Eight cohort studies across six different cancer types showed that patients with detectable ctDNA after surgery had an increased risk of cancer recurrence. This suggests that early postoperative time points could be used […]
Impact of Guideline Adherence on the Prognosis of Stage B Hepatocellular Carcinoma
South Korean patients with Barcelona Clinic Liver Cancer (BCLC) stage B hepatocellular carcinoma (HCC) showed significant variations in adherence to treatment guidelines over the study period of 2008-2016. Adherence to guidelines, particularly those recommended by the European Association for the Study of the Liver (EASL) and the American Association for the Study of Liver Diseases […]
Faculty Perception Misaligned with Resident Behaviors in the Operating Room
Researchers conducted a study to determine if faculty perception aligned with resident self-perception of intraoperative behaviors in order to enhance intraoperative learning. They found that faculty were not able to accurately perceive residents’ motivational style, as evidenced by the lack of correlation between resident self-perception and faculty perception of resident behavior in eight out of […]