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Best Papers in General Surgery
The five that matter, every day.
The study explores terminology, classification, and significance of dysplasia and early carcinoma in the gallbladder and bile ducts. Most precursor lesions and early cancerous changes are clinically undetectable. Low-grade dysplasia is challenging to define and lacks clinical significance, but additional sampling is required to exclude…
A retrospective chart review of 43 cases of Spigelian hernias over a 10-year period found that a laparoscopic approach was the preferred method of repair in 74% of cases. The predominant hernial content was fat only, and 65% of cases had a history of prior…
Prophylactic mesh augmentation in emergency laparotomy closure was evaluated through a meta-analysis of randomized controlled trials. After reviewing 33 studies, four were included in the analysis, involving 464 patients. The results showed a significant decrease in incisional hernia incidence when mesh reinforcement was used (OR…
The study examined the relationship between different adipose tissue parameters and the incidence of incisional hernias (IH) after abdominal surgeries, as well as the outcomes of hernia repair. Thirteen studies were analyzed, showing that increased visceral and subcutaneous fat volume were associated with a higher…
A recent study conducted at a German pancreatic center investigated the role of microbiota in perioperative outcomes of pancreatic head resections. The study utilized 16s rrna sequencing and microbial culturing to analyze samples collected from various gastrointestinal sites of 101 patients undergoing surgery. The findings…
Analysis of the SENORITA trial comparing laparoscopic standard gastrectomy (LSG) and laparoscopic sentinel node navigation surgery (LSNNS) for early gastric cancer (EGC) found that there was no significant difference in the 5-year disease-free survival (DFS), overall survival (OS), or disease-specific survival (DSS) between the two…
Researchers analyzed a large number of tissue samples and found that gad2 immunohistochemistry is a highly specific diagnostic marker for neuroendocrine neoplasms of the pancreas. The expression of gad2 was only observed in a few normal cell types, making it a potential diagnostic tool. It…
The study reveals that the number of surgeon-scientists funded by the National Institutes of Health (NIH) in the US has increased, with a higher proportion engaged in basic science research rather than clinical research. In fiscal year 2022, 1,324 surgeon-scientists were awarded $1.3 billion in…
Large language model GPT-4, specifically the chatbot version ChatGPT, demonstrates near or above human-level performance on surgical knowledge assessments from two widely used question banks. In open-ended questions, ChatGPT answers accurately to 47.9% and 66.1% of questions, while for multiple-choice questions, it achieves accuracy rates…
The study aimed to identify predictors for spontaneous passage of foreign bodies in adults by analyzing their characteristics, such as type, length, and location. A retrospective 12-year study included 365 patients, and the overall rate of spontaneous passage was 53.7%. Food impaction had a passage…
