Newsletter
Best Papers in General Surgery
The five that matter, every day.
The OPAXX study aims to determine the rate of successful organ preservation in patients with rectal cancer who have a good clinical response after neoadjuvant therapy. The study, conducted in the Netherlands, will include 168 patients who will be randomized into two parallel single-arm phase…
The study investigated risk factors associated with intra-abdominal abscesses (IAA) following major operative liver trauma. Based on a retrospective multi-center study involving 372 patients, it was found that patients with penetrating trauma, activation of intraoperative massive transfusion protocol, biloma/bile leak, longer hospital length of stay,…
Patients with diffuse involvement of the gallbladder mucosa have aggressive tumor biology and worse overall survival compared to those with focal disease. This retrospective study analyzed 63 patients with non-metastatic gallbladder adenocarcinoma and found that 50.7% had diffuse cancer. There was no difference in the…
In a study comparing open surgery, laparoscopy with intracorporeal anastomosis, and laparoscopy with extracorporeal anastomosis for oncological right hemicolectomy, researchers found that laparoscopic approaches had significantly lower complication rates than open surgery. The duration of surgery was longer in the laparoscopic groups, but the length…
Researchers have made advances in the management of gallbladder polyps through the establishment of predictive models and the use of gallbladder-preserving polypectomy procedures. These procedures allow for the eradication of lesions while preserving a functional gallbladder, providing benefits to patients with benign polyps. However, further…
In analyzing 1,979 trauma deaths from 2015 to 2022, researchers assessed the impact of quarterly preventable mortality reviews (PMR) on reducing preventable or potentially preventable deaths in the Arkansas Trauma System (ATS). Results showed a progressive decrease in preventable deaths and opportunities for improvement (OFIs).…
Empiric cryoprecipitate transfusion as an adjunct to a balanced transfusion strategy did not improve survival or reduce transfusion requirements in severely injured bleeding trauma patients. The study found no significant differences in demographics, arrival physiology, laboratory values, or injury severity between the groups receiving cryoprecipitate…
The study aimed to identify predictive factors for early recurrence and survival outcomes in colorectal cancer patients with liver and peritoneal metastases who underwent combined liver resection, cytoreductive surgery, and hyperthermic intraperitoneal chemotherapy. The results showed that patients with advanced primary tumors (PT4 and/or PN2…
A retrospective cohort study investigated the use of serum carcinoembryonic antigen (CEA) as an alternative prognostic marker for overall survival in patients with localized pancreatic adenocarcinoma and non-elevated levels of carbohydrate antigen 19-9 (CA19-9). The study found that elevated CEA at baseline was independently associated…
A study analyzing hospitalizations for ileostomy creation found that care fragmentation, defined as receiving care at a different facility than where the index ileostomy was performed, was associated with higher mortality rates and increased risk of postoperative complications such as cardiac, respiratory, infectious, and thromboembolic…
