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Best Papers in General Surgery
The five that matter, every day.
The study compared the effects of ampulla-guided realignment and conventional gallbladder triangle anatomy in difficult laparoscopic cholecystectomy. Data from 100 patients undergoing the procedure were retrospectively analyzed. The experimental group (ampulla-guided realignment) showed shorter operation time, reduced blood loss, lower postoperative complications, shorter hospitalization, and…
A randomized controlled trial assessed the efficacy of rectal indomethacin in preventing post-operative hyperamylasemia (POH) following pancreatoduodenectomy (PD). The study included 44 patients who either received 100mg of indomethacin per-rectally or standard care. The intervention arm had a significantly lower incidence of POH (28.6% vs.…
This study aimed to assess the prevalence of somatic symptom severity (sss), depression, and anxiety in surgical inpatients with different diagnostic groups of abdominal pain. The results showed that somatic symptoms were common, with 52% having moderate and 19.6% having severe sss. There was a…
Rectal cancer patients with a positive circumferential resection margin (CRM) due to direct tumor involvement face a worse prognosis than those with indirect causes. Analyzing 1460 cases, 85 had positive CRMs, with direct involvement linked to increased local recurrence. Kaplan-Meier analysis showed better overall and…
Ultra-low-pass whole-genome sequencing (ULP-WGS) of circulating tumor DNA (ctDNA) can provide clinically relevant information about tumor biology in patients with hepatocellular carcinoma (HCC) under systemic treatment. The presence of ctDNA and the loss of specific genomic regions (5q and 16q) were identified as independent predictors…
With a higher mortality rate compared to other cancers, pancreatic cancer poses significant challenges. However, there have been improvements in survival rates, although at a slower pace. Researchers have investigated multimodal treatment approaches involving chemotherapy, surgery, and radiotherapy. Recent advancements in treatment regimens show promise…
Colorectal carcinoma with sarcomatoid components is a rare and aggressive subtype of colorectal cancer. In this study, researchers reported 15 cases of this subtype and reviewed the existing literature. The tumors were predominantly found in the rectosigmoid region and presented with symptoms such as abdominal…
The study investigated the impact of endoscopic ultrasound (EUS) in the liver transplantation (LT) work-up for patients with unresectable perihilar cholangiocarcinoma (PCCA). EUS screenings were performed on a selected group of patients, and the primary outcome was the number of patients precluded from further screening…
The systematic review and meta-analysis of studies investigating the association of surgical technique with outcomes for colorectal liver metastases (crlm) found that anatomic resection (AR) was associated with improved liver-specific disease-free survival (DFS) and overall DFS in patients with mutras tumors. Specifically, AR resulted in…
The course of the segment 4 hepatic artery affects the proximal ductal margin status in right hepatectomy for perihilar cholangiocarcinoma. The study found that the l-up type of the artery, running along the left cranial position of the umbilical portion of the left portal vein,…
