BMJ Open6 Jan 2024
The study evaluated the utilization and outcomes of endoscopic retrograde cholangiopancreatography (ERCP) procedures in the first advanced endoscopy center in Palestine. A total of 1909 procedures on 1303 patients were included, with an overall complication rate of 5%. The primary adverse events were post-ERCP pancreatitis…
Intestine and Lower Gastrointestinal Tract6 Jan 2024
Researchers analyzed retrospective data from high-resolution anorectal manometry and patient-completed bowel habit and symptom diaries to evaluate the usefulness of the diary as a screening tool for disordered rectoanal coordination (DRC). They found that patients with a dyssynergic pattern (DP) during manometry had a higher…
J Clin Gastroenterol6 Jan 2024
The study analyzed trends in hospitalizations for hepatocellular carcinoma (HCC) in the United States between 2011 and 2017. The researchers found an increase in HCC-related admissions over the years, with a decrease in inpatient mortality rates. However, there was a significant rise in the financial…
J Surg Res6 Jan 2024
A retrospective cohort study analyzed molecular profiling and mutation rates in stage IV colorectal cancer (CRC) patients. The study found significant increases in molecular testing rates for microsatellite instability (MSI), KRAS, and BRAF mutations over time. Black patients had higher odds of testing for MSI…
J Surg Res6 Jan 2024
A retrospective review of 796 patients undergoing parathyroidectomy with intraoperative parathyroid hormone (iPTH) monitoring for primary hyperparathyroidism identified 18 patients with parathyroid carcinoma. The study found that patients who achieved a >50% decrease in iPTH levels into the normal reference range had a higher rate…
JAMA Surg5 Jan 2024
Most US hospital networks have low-volume hospitals performing elective surgeries that are associated with inferior outcomes. However, within these networks, there are other hospitals that meet volume standards and are located within a reasonable distance from patients' homes. The study found significant variation in rates…
J Am Coll Surg5 Jan 2024
Expert consensus was achieved on the definition of textbook oncologic outcomes (TOO) in cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) for colorectal peritoneal metastasis. The consensus criteria included the absence of unplanned re-operations, severe postoperative complications, unplanned readmissions, 90-day postoperative mortality, and contraindications for…
Ann Surg Oncol5 Jan 2024
Patients with pancreatic adenocarcinoma who undergo distal pancreatectomy and receive neoadjuvant chemotherapy (NAT) are 73% more likely to develop postoperative deep venous thrombosis (DVT) compared to those who undergo upfront resection. This association is significant and highlights the need to prioritize high-risk patients for extended…
Ann Surg Oncol5 Jan 2024
Patients with mutras colorectal liver metastases (crlm) may benefit from anatomic resection (AR) compared to nonanatomic resection (NAR), according to a systematic review and meta-analysis. The study found that AR was associated with a significant improvement in liver-specific disease-free survival and overall disease-free survival among…
Ann Surg Oncol5 Jan 2024
The study demonstrates that delta radiomic features (DRFs), when combined with clinical variables, are effective in predicting resection margin status (RMS) and overall survival (OS) in neoadjuvant-treated pancreatic cancer patients. The models outperform clinical feature-based and other radiomics feature-based models in predicting OS, disease-free survival…