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Best Papers in General Surgery
The five that matter, every day.
In a non-inferiority RCT comparing low-pressure pneumoperitoneum (LPP) with deep neuromuscular blockade (NMB) to standard pressure pneumoperitoneum (SPP) with moderate NMB for laparoscopic cholecystectomy, researchers found similar surgeon satisfaction scores between groups. This suggests that LPP with deep NMB is not inferior to SPP with…
In a Delphi survey involving 43 global obesity experts, unanimous consensus (≥70% agreement) was achieved on 15 essential definitions and reporting standards in metabolic bariatric surgery (MBS). Notable agreement (95/121 statements) covered preferred surgical procedures like Roux-en-Y gastric bypass and sleeve gastrectomy. Moderate consensus existed…
Examining 161 patients with colorectal liver metastases (CRLM), researchers investigated the safety and efficacy of simultaneous hepatic resection (HR) and ablation. With 77.6% having bilobar disease and 57.1% having ≥5 tumors, the combined procedure demonstrated acceptable safety and durable long-term survival (median 38.2 months, 5-year…
Investigating the combination of pelvic exenterations and cytoreductions in T4 rectal cancers with peritoneal metastasis, a study on 39 patients (median age 35) revealed safety in terms of morbidity (18% major complications). Although achieving CC-0 in 97.4%, hyperthermic intraperitoneal chemotherapy was administered to 15 patients.…
In a Danish cohort study emulating a randomized controlled trial, researchers assessed adjuvant chemotherapy's impact on node-negative (PN0) and node-positive (PN+) pancreatic cancer survival after surgery. Among PN0 patients, adjuvant therapy showed no significant 2-year survival difference (-2.2%). For PN+ individuals, a 9.9% improvement in…
Examining three popular AI text-to-image generators, the study assessed the demographic accuracy of surgeon representations. It found these models overwhelmingly portrayed surgeons as white and male, reinforcing societal biases. Trainees, especially non-white and female, were underrepresented. While one model reflected attending surgeons accurately, all underestimated…
In addressing the surge in small bowel neuroendocrine tumors (SB-NETs), this study underscores surgery's pivotal role. Emphasizing multifocal assessment and mesenteric-sparing strategies, it delineates eight systematic steps for surgical planning. While stressing the necessity of achieving oncological control, some controversies persist, notably regarding resection in…
Analyzing 120 elderly esophageal cancer patients (Stage I-IV), the study revealed a 5-year overall survival rate of 45.2%. Lower body mass index, reduced pre-albumin levels, advanced tumor stage, postoperative pulmonary issues, and specific treatments significantly influenced outcomes. Despite a median 31-month follow-up, esophagectomy proved safe…
Analyzing clinically node-negative gastric cancer patients, the study investigated the influence of time from diagnosis to surgery. Among 1824 patients, those with a longer interval (≥ 8 weeks) experienced less lymph node upstaging. Although overall survival differences appeared in Kaplan-Meier curves, multivariable analysis didn't associate…
Analyzing data from 976 patients with synchronous colorectal liver metastases, researchers compared simultaneous and staged resections. Simultaneous resection, beneficial for low to moderate tumor burden and node-negative right-sided primary tumors, showed increased complications in high tumor burden cases. Staged resection demonstrated better outcomes for patients…
