Endoscopic ultrasonography (EUS) is a sensitive method for identifying residual rectal neuroendocrine tumors (NETs) post-resection. EUS detection, with a high sensitivity of 94%, is superior to visual detection. Salvage endoscopic treatment, incorporating EUS, is safe and effective in managing incompletely resected NETs, with no recurrence observed in patients during follow-up. EUS shows promise in accurately […]
Category: Surgical Endoscopy
Pre-operative Biliary Drainage Increases Complications in Resectable Periampullary Lesions
Pre-operative biliary drainage significantly raised complication rates in periampullary lesion patients, as shown by a meta-analysis including 35 studies and 2 randomized trials with 12,641 patients. Results revealed higher overall complication rates, increased delayed gastric emptying post-surgery, and a significant rise in wound infections post-operatively in the drainage group. These findings caution against routine pre-operative […]
Establishment of a patient-specific organoid model for timely pancreatic cancer treatment
Patient-derived organoids (PDOs) from EUS-guided biopsies show high success rate in establishing models for pancreatic ductal adenocarcinoma (PDAC). PDAC PDOs accurately reflect genetic alterations in the original tumors and predict drug sensitivity, including resistance to nab-paclitaxel. This innovative model enables rapid testing of multiple therapeutic drugs, offering a personalized “patient avatar” for timely clinical decision-making […]
French Intergrup Clinical Practice Guidelines for Ampullary Tumors
French intergroup guidelines provide recommendations for accurate diagnosis, treatment, and follow-up of ampullary tumors based on expert opinions and recent literature review. Emphasizing multidisciplinary approach, guidelines suggest endoscopic papillectomy or surgical papillectomy for adenoma, and pancreaticoduodenectomy for carcinoma. Adjuvant monochemotherapy or polychemotherapy is recommended for aggressive tumors. Long-term follow-up is crucial for 5 years. Guidelines […]
Surgical Repair of Colonic Perforations Shows Comparable Outcomes
Patients who underwent surgical repair for colonoscopy-related perforations had similar short-term morbidity and mortality rates compared to those undergoing elective or emergency colorectal surgeries. Mortality rate was 4.1%, with no significant difference among open colectomy, suturing, and laparoscopic colectomy. Laparoscopic colectomy had significantly lower morbidity rates. Patients with iatrogenic colonic perforation had better outcomes than […]
Increased Risk of Colorectal Neoplasia After Polyp Removal
High-risk adenomas and serrated polyps significantly increase the risk of colorectal cancer within 3 years post-polypectomy. Surveillance colonoscopy is vital for preventing subsequent cancer, especially for patients with high-risk polyps. The study highlights the importance of early surveillance within 3 years for patients with high-risk polyps, suggesting that incomplete resection and missed lesions contribute to […]
Antegrade Balloon Dilatation: Superior Approach for Choledocholithiasis
Antegrade balloon dilatation during laparoscopic cholecystectomy showed significantly fewer interventions and reduced treatment time compared to endoscopic retrograde cholangiography in patients with acute obstructive common bile duct stones. The ‘abd-during-che’ technique had a lower overall complication index and fewer major complications, highlighting its potential as an alternative one-stop-shop treatment option for this patient population. Journal […]
Comparable Long-Term Survival Prognoses in Gastrointestinal Neuroendocrine Neoplasms
Endoscopic treatment and surgery show similar overall and cancer-specific survival rates in gastrointestinal neuroendocrine neoplasms. Endoscopic treatment may offer a better cancer-specific survival in certain cases such as stage I tumors and those smaller than 10mm. Both treatment options are viable for patients, with endoscopic treatment as a potential alternative for those hesitant about surgery. […]
High Rates of Colitis-Associated Post-Colonoscopy Colorectal Cancers
Analysis reveals 61% of inflammatory bowel disease-related colorectal cancers were post-colonoscopy, often due to delays in surveillance and missed lesions in areas of inflammation. Proactive strategies are needed to reduce endoscopic burden and improve surveillance adherence, as traditional methods show limitations in detecting aggressive cancer evolution. Molecular biomarkers may enhance risk assessment in future clinical […]
Factors influencing peroral endoscopic myotomy outcomes
Meta-analysis identifies that sigmoid esophagus, type of achalasia, and prior treatments impact the success of peroral endoscopic myotomy (POEM) for achalasia. Specifically, type I and III achalasia, sigmoid esophagus, and past heller myotomy or balloon dilation correlate with higher failure rates. Conversely, type II achalasia shows better response rates. This data can aid in treatment […]