The hepatic blood supply, a crucial aspect of liver surgery and transplantation, has undergone significant reorientations in recent years. Despite advancements, gaps in our understanding persist, impacting outcomes in living donor liver transplantation. This review delves into the complexities of portal hemodynamics in liver disease, exploring its role in liver regeneration and transplantation. Journal Article […]
Category: Transplant Surgery
Bariatric surgery post-liver transplantation in Belgium: Significant weight loss and metabolic improvements observed with favoring sleeve gastrectomy.
Bariatric surgery post-liver transplantation in Belgium showed significant and sustained weight loss, resolution of metabolic dysfunction-associated liver disease, and favorable metabolic outcomes. Sleeve gastrectomy was the favored procedure, leading to improved clinical and biochemical markers. Despite a small sample size, the results suggest the safety and efficacy of bariatric surgery in liver transplant recipients. Journal […]
Immunosuppressive Induction Agents in Liver Transplantation: No Impact on Incisional Hernia Development
Despite the technical complexity of liver transplantation and the high incidence of incisional hernias, a retrospective cohort study found that the specific immunosuppressive induction agent administered during surgery did not affect the development of hernias. However, obesity and postoperative seroma of the abdominal wall were identified as potential risk factors. The overall incisional hernia rate […]
Sleeve Gastrectomy: A Vital Reducer of Liver Transplantation Need in Non-Alcoholic Steatohepatitis Patients
Simulation of 20,000 obese patients with non-alcoholic steatohepatitis found that sleeve gastrectomy (SG) led to a gain of 14.3 years compared to medical weight management (MWM), with only 5% of SG patients requiring liver transplantation (LT) after one year, compared to 9% in the MWM group. SG reduced the need for LT in patients with […]
Crucial Role of EUS in LT Workup for Unresectable pCCA
EUS plays a crucial role in the liver transplantation (LT) workup for patients with unresectable perihilar cholangiocarcinoma (pCCA). In a nationwide study, EUS identified malignant nonregional lymph nodes (LNs) in 4% of patients potentially eligible for LT. Surgical staging confirmed malignancy in 14% of patients with nonregional LNs. The study emphasizes the limited but clinically […]
Long-term Mortality Risk in Total Pancreatectomy Patients with Islet Autotransplant
Total pancreatectomy with islet autotransplant (TPIAT) for pancreatitis patients has a 10-year survival rate of 85.2% and a 15-year rate of 76.2%. Most deaths (53 out of 89) were possibly related to TPIAT, with causes including chronic gastrointestinal issues, malnutrition, and diabetes. Younger age, longer disease duration, and recent procedures were linked to lower mortality. […]
Comparison of laparoscopic liver resection outcomes in centers with and without liver transplant programs
Centers with liver transplant programs in France perform more difficult laparoscopic liver resections for hepatocellular carcinoma in cirrhotic patients compared to centers without transplant programs. Despite this complexity, both types of centers showed comparable safety and quality of care in terms of postoperative severe morbidity and mortality rates, demonstrating that all centers can achieve good […]
Bariatric Surgery in ESRD Patients on Dialysis: Safety and Outcomes in the Transplant Era
Patients with end-stage renal disease (ESRD) on dialysis who underwent bariatric surgery experienced longer operative times and increased postoperative complications compared to those without renal disease. The study, analyzing data from the 2015-2020 MBSAQIP database, found that laparoscopic sleeve gastrectomy (LSG) and laparoscopic Roux-en-Y gastric bypass (LRYGB) were safe procedures for ESRD patients seeking kidney […]
Bariatric Surgery Facilitates Renal Transplantation in Patients with End-Stage Renal Disease and Obesity
Bariatric surgery (BS) can be a beneficial intervention for patients with obesity and end-stage renal disease (ESRD) who require renal transplantation (RT). A review of 31 patients referred for BS found that those who underwent the procedure had increased access to RT and experienced safe and effective outcomes. These findings suggest that the use of […]
Endoscopic Ultrasound Identifies Malignant Lymph Nodes in LT Work-up for Unresectable Perihilar Cholangiocarcinoma
The study investigated the impact of endoscopic ultrasound (EUS) in the liver transplantation (LT) work-up for patients with unresectable perihilar cholangiocarcinoma (PCCA). EUS screenings were performed on a selected group of patients, and the primary outcome was the number of patients precluded from further screening due to malignant lymph nodes (LN). The study found that […]