Analyzing 1020 patients with gastric signet-ring cell cancer (GSRCC), researchers investigated the relationship between the number of examined lymph nodes (ELNs) and prognosis. X-tile analysis determined the optimal ELN cutoff as 22. Patients with more than 22 ELNs demonstrated higher 5-year overall survival (66.9% vs. 74.9%). Multivariate analyses revealed that a higher number of ELNs (44-52) was associated with superior overall survival, emphasizing the importance of thorough lymph node examination for improved prognosis in GSRCC.
Journal Article by Jiang Y, Shao X (…) Tian Y et 4 al. in Ann Surg Oncol
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