Novel minimally invasive procedures for gastroesophageal reflux disease show promising outcomes, impacting patient selection and surgical approaches.

• Esophyx and Linx provide long-lasting symptom relief, with sustained quality of life improvements for chronic GERD patients.
• Stretta shows clinically significant long-term effects on proton pump inhibitor usage and pH monitoring but has limited follow-up data.

Surgeons should consider patient characteristics, such as hiatal hernias and PPI response, when selecting these procedures.

• Muse and Refluxstop need better data for clearer clinical roles.