Using whole blood for prehospital transfusions in trauma patients does not significantly decrease 30-day mortality compared to blood components.

• 30-day mortality was 25.9% for whole blood vs. 20.5% for components (adjusted odds ratio 1.24, p=0.24).
• No significant differences in adverse events between groups were noted.

Surgeons should consider these findings when deciding on prehospital transfusion strategies for hemorrhagic shock patients.

• Storage age of whole blood (1-14 days vs. 15-21 days) did not impact 30-day mortality significantly.