Correlation between main and minor lesions of synchronous multiple gastric neoplasms

Researchers analyzed data from patients with early gastric cancer (EGC) who underwent endoscopic submucosal dissection (ESD) to assess the correlation between main and minor lesions of synchronous multiple gastric neoplasms (SMGNs). Among the 1013 post-ESD cases examined, 95 cases had SMGN. The study revealed a similarity in pathological type (rs = 0.37) and a positive correlation in infiltration depth (rs = 0.58) between main and minor lesions. The diameter sizes of the main and minor lesions were significantly different, with a linear correlation observed. Similarities were also found in the spatial distribution and gross endoscopic morphology of the lesions. The study suggests a significant positive correlation between main and minor lesions in terms of pathological stage and depth of infiltration.