Findings indicate that lymph node dissection (LND) during upfront gastrectomy significantly impacts prognostic outcomes for gastric adenocarcinoma (GAC) patients. The study recommends total lymph node (TLN) counts of ≥18 for detecting positive nodes and ≥23 for identifying N3 status. Furthermore, a negative lymph node count (NLN) >9 correlates with better survival in N+ GAC patients, requiring a TLN ≥20 for effective staging. Ultimately, D2 dissection is endorsed as superior for LND effectiveness.
Journal Article by Lee CH, Lee HT (…) Lin CS et 3 al. in Ann Ital Chir