Sequential Treatment Outperforms Open Abdomen Approach for Duodenal Leakage-Induced Intra-Abdominal Bleeding

A cohort study examined treatments for intra-abdominal bleeding caused by duodenal leakage. The two approaches were “Sequential Treatment” (ST), which combines arterial embolization and drainage, and “Open Abdomen” (OA), a simultaneous method. ST had a lower mortality rate (28.2% vs. 51.3%) and better initial hemostasis success (94.4% vs. 77.8%) compared to OA. After propensity score matching, ST remained superior, reducing mortality and rebleeding. The study suggests that ST, involving arterial embolization and subsequent drainage, may be more effective in lowering mortality in this context.