In a randomized trial involving 102 patients with chronic liver disease undergoing hepatectomy, remote ischemic preconditioning’s anticipated liver-protective benefits were not realized. Despite inducing preconditioning through upper extremity cycles of ischemia and reperfusion, the study showed no significant reduction in postoperative transaminase levels. The results suggest limited efficacy in mitigating ischemia-reperfusion injury, challenging the application of this technique in hepatectomy for patients with chronic liver conditions.
Journal Article by Hardt JLS, Pohlmann P, Reissfelder C and Rahbari NN in BMC Surg
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