In a retrospective analysis of 168 biliary tract carcinoma patients post-surgery, 83.9% received adjuvant chemotherapy, while 16.1% did not. Notably, hepatectomy with extrahepatic bile duct resection (BDR) significantly hindered chemotherapy administration compared to other surgeries. Refractory bile leak, primarily post hepatectomy with BDR, was a common reason for non-administration. Multivariate analysis identified hepatectomy with BDR and preoperative anemia as independent factors associated with the difficulty of adjuvant chemotherapy, emphasizing the need for alternative strategies in such cases.
Journal Article by Sumiyoshi T, Uemura K (…) Takahashi S et 9 al. in Langenbecks Arch Surg
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