Smoking status predicts treatment failure in anti-reflux mucosectomy for gastroesophageal reflux disease

The study evaluated the outcomes and predictors of treatment failure in patients undergoing anti-reflux mucosectomy for gastroesophageal reflux disease. The results showed that the procedure significantly improved quality of life, with symptom improvement and resolution in a majority of patients. However, symptom resolution did not always correlate with objective reflux control. Current smoking status was identified as a predictor of treatment failure, suggesting the need to consider smoking in patient selection.