The study evaluated the influence of tumor size on the prognosis of patients with esophageal squamous cell carcinoma (ESCC) undergoing esophagectomy after neoadjuvant chemotherapy. A total of 272 patients were categorized based on tumor size, with 36mm being the cut-off. Patients with tumor size ≥ 36mm had worse histological response and deeper tumor invasion. In patients with stage pt0-1, pt2, and pt4 ESCC, there were no significant differences in overall survival rates between the two groups. However, in patients with stage pt3 ESCC, tumor size ≥ 36mm was an independent risk factor for poorer survival, especially when accompanied by lymph node metastasis.
Journal Article by Koterazawa Y, Oshikiri T (…) Kakeji Y et 9 al. in Ann Surg Oncol
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