Neoadjuvant Chemotherapy Does Not Increase Postoperative Complications in Gastric Adenocarcinoma

The study compared postoperative complications between neoadjuvant chemotherapy and upfront surgery in gastric adenocarcinoma patients in Finland. Analyzing data from 769 patients, the study found that neoadjuvant chemotherapy did not increase major postoperative complications, including pneumonia, anastomotic complications, wound complications, or other complications. The results suggest that neoadjuvant therapy is not associated with increased postoperative complications, reoperations, or short-term mortality in gastric adenocarcinoma patients.