Researchers analyzed data from 474 patients with superficial esophageal squamous cell carcinoma (ESCC) to identify lymph node metastasis (LNM) risk factors. For intramucosal cancer, LNM prevalence was 3.29%, increasing to 26.40% for submucosal cancer. Tumor size, invasive depth, differentiation, growth pattern, budding, and lymphovascular invasion correlated significantly with LNM. A nomogram incorporating these factors demonstrated good predictive accuracy in both training (AUC = 0.789) and validation sets (AUC = 0.827). The nomogram aids in assessing LNM risk for better treatment decisions in superficial ESCC patients after endoscopic resection.
Journal Article by Wang J, Zhang X (…) Yang JL et 3 al. in World J Gastroenterol
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