Recurrence after surgery for colorectal liver metastases (CRLM) is common within two years, but there is no established guidance on follow-up methods and intensity. A systematic review of 25 articles involving 9,945 patients revealed wide variation in follow-up methods, with CT as the most common imaging modality and CEA as the most common blood test. Overall survival ranged from 39% to 78.1% among the studies. There is a lack of strong evidence to support intensive follow-up, and the benefits of long-term follow-up remain unclear. Future research should focus on high-quality prospective studies.
Review by Jones A, Findlay A (…) Pathak S et 4 al. in Eur J Surg Oncol
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