Long-Term Oncologic Outcome Similar Between Proximal Gastrectomy and Total Gastrectomy for Upper-Third AGC and EGJ Cancer

Proximal gastrectomy (PG) and total gastrectomy (TG) for upper-third advanced gastric cancer (AGC) and Siewert type II esophagogastric junction (EGJ) cancers yield similar overall survival rates (61.7% vs. 68.3%) and recurrence-free survival rates (86.7% vs. 83.3%). PG group had eight recurrences, but operation method was not identified as a prognostic factor of tumor recurrence in multivariate analysis. Results suggest long-term oncologic outcomes for patients undergoing PG are comparable to TG for upper-third AGC and EGJ cancer.