Low Rates of Metastases in Mucosal Esophageal Adenocarcinoma with Poor Differentiation

Patients with mucosal esophageal adenocarcinoma and poor differentiation had low rates of metastases after endoscopic resection, even when additional risk factors were present. Metastasis rates were 4.0% for single risk factor patients and 20.0% for those with additional risk factors. Overall death rates were 28.0% and 20.0% for the respective groups. A conservative approach may be justified for this patient population, pending further prospective data.