Risk Factors for Perforation in Gastric Endoscopic Submucosal Dissection

Study identified risk factors for intraoperative and delayed perforations in gastric endoscopic submucosal dissection for early gastric cancer. Intraoperative perforation occurred in 2.2% of patients, necessitating emergency surgery in 0.04% of cases, while delayed perforation occurred in 0.4% of patients, with emergency surgery required in 0.12% of cases. Factors like location in upper or middle third of the stomach, remnant stomach or gastric tube, procedure time ≥100 min, tumor size >35 mm, and BMI <18.5 kg/m were significantly correlated with intraoperative perforation.