Defining Optimal CA19-9 Response in Locally Advanced Pancreatic Cancer

Minimum CA19-9 decrease of ≥40% and optimal decrease of ≥60% after induction chemotherapy are independent predictors for prolonged overall survival in patients with locally advanced pancreatic cancer, particularly when CA19-9 levels are elevated at baseline. These thresholds can guide treatment decisions during early response evaluation.

Journal Article by Seelen LWF, Doppenberg D (…) Besselink MG et 25 al. in Ann Surg

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