Minor impact of anastomotic leakage on long-term male urinary and sexual function
Anastomotic leakage after anterior resection for rectal cancer has a minor negative impact on male urinary function, leading to increased urinary incontinence rates. However, it does not significantly affect sexual function or increase risks of urinary frequency, permanent urinary catheter use, or sexual inactivity in the long term.
Removing the rectal tumor and liver spread in one operation did not clearly raise complications or hurt survival compared with two separate operations, a French national study found.
A Japanese randomized trial found that a 14-day schedule of trifluridine-tipiracil plus bevacizumab keeps patients with metastatic colorectal cancer alive as long as the standard 28-day schedule, with far less toxicity.