Feasible and safe, hepatic arterial infusion pump chemotherapy combined with systemic chemotherapy (HAIP-SYS) for colorectal liver metastases (CRLMs) showed promising results in a phase II study in the Netherlands. With a completion rate of 90% for two cycles, it demonstrated favorable disease control rates at first radiological evaluation and six months post-treatment. Although some patients experienced grade 3 complications and chemotherapy toxicity, the study supports further investigation into its oncological benefits in a phase III trial.
Journal Article by Krul MF, Kok NFM (…) Kuhlmann KFD et 18 al. in Br J Surg
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