Hyperthermic intraperitoneal chemotherapy (HIPEC) significantly improved overall survival and reduced recurrence rates in both prophylactic and therapeutic settings for peritoneal carcinomatosis of gastric origin. This systematic review and meta-analysis of randomized trials highlights the efficacy of HIPEC as a safe and effective tool for prophylaxis and a promising resource for treatment, emphasizing the need for further large-cohort studies to provide definitive recommendations.
Review by Stefano M, Perrina D (…) Catena F et 13 al. in J Gastrointest Surg
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