Impact of Hazard Function Analysis on Prognosis After Colorectal Cancer Recurrence
Hazard function analysis provided new insights into patient prognosis post colorectal cancer recurrence, revealing a peak risk of death at 2.9 years post-recurrence. Factors like metastatic organs, treatment type, and recurrence interval influenced short-term survival. The method offers an alternative to mean survival time and helps predict mortality risk changes over time.
Removing the rectal tumor and liver spread in one operation did not clearly raise complications or hurt survival compared with two separate operations, a French national study found.
A Japanese randomized trial found that a 14-day schedule of trifluridine-tipiracil plus bevacizumab keeps patients with metastatic colorectal cancer alive as long as the standard 28-day schedule, with far less toxicity.