Neoadjuvant chemotherapy demonstrates better long-term survival outcomes compared to neoadjuvant chemoradiotherapy. Although the latter may exhibit a higher pathological complete response rate, it does not necessarily translate to improved survival. Additionally, neoadjuvant chemoradiotherapy is associated with higher 30-day mortality and unclear postoperative complications, potentially compromising patients’ quality of life.
Journal Article by Csontos A, Fazekas A (…) Papp A et 6 al. in World J Gastroenterol
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