A single-center study on resected gastroesophageal junction adenocarcinoma showed improved operative outcomes over time, with type I tumors linked to poorer survival. Most patients received neoadjuvant therapy and underwent minimally invasive surgery, resulting in low mortality rates and decreased morbidity. Signet ring tumors were more common in type III cases, influencing overall survival. Pathologic features did not significantly differ among Siewert subtypes.
Journal Article by Stiles ZE, Hagerty BL (…) Kukar M et 3 al. in J Gastrointest Surg
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