Early postoperative CRP levels are a key predictor of anastomotic leakage after esophagectomy, with a cutoff value of < 222 mg/l on day 2 showing 81% sensitivity and 88% specificity. Other biomarkers like WBC counts and albumin levels had limited diagnostic accuracy. A NUN score >10 on day 4 was unreliable. CRP < 127 mg/l on day 5 can safely guide discharge decisions, helping optimize patient management post-surgery.
Review by Van Daele E, Vanommeslaeghe H (…) Pattyn P et 3 al. in J Gastrointest Surg
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