Risk Factors for Anastomotic Leak After Esophagectomy

An analysis of 4,331 patients undergoing esophagectomy revealed smoking, frailty index, white blood cell count, mckeown esophagectomy, and platelet counts were associated with anastomotic leak. Results showed increased odds of leak with smoking, frailty index scores of 1 or 2, and specific surgical techniques, while higher platelet counts were slightly protective. These findings offer crucial insights to guide preoperative strategies and improve patient outcomes.