Larger tumor size and elevated serum chromogranin A levels are predictive of metastatic disease in patients with gastroenteropancreatic neuroendocrine tumors undergoing DOTATATE imaging. Patients with primary tumor size ≥2 cm, serum CGA level ≥150 ng/ml, and tumor grade g2 are at higher risk of metastases, indicating the potential use of these factors in identifying patients who would benefit from DOTATATE imaging for complete staging.
Journal Article by Labora A, Shimizu T (…) Donahue TR et 7 al. in Ann Surg Oncol
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