Endoscopic submucosal dissection outperforms endoscopic mucosal resection for rectal lesions involving the dentate line

Endoscopic submucosal dissection (ESD) demonstrated superior efficacy over endoscopic mucosal resection (EMR) in treating rectal lesions involving the dentate line. ESD had higher en bloc and complete resection rates, lower recurrence rates, and higher curative rates, especially for low-risk adenocarcinomas. ESD should be considered the preferred treatment for these lesions based on the study’s findings.