Endoscopic submucosal dissection outperforms endoscopic mucosal resection for rectal lesions involving the dentate line
Endoscopic submucosal dissection (ESD) demonstrated superior efficacy over endoscopic mucosal resection (EMR) in treating rectal lesions involving the dentate line. ESD had higher en bloc and complete resection rates, lower recurrence rates, and higher curative rates, especially for low-risk adenocarcinomas. ESD should be considered the preferred treatment for these lesions based on the study’s findings.
Removing the rectal tumor and liver spread in one operation did not clearly raise complications or hurt survival compared with two separate operations, a French national study found.
A Japanese randomized trial found that a 14-day schedule of trifluridine-tipiracil plus bevacizumab keeps patients with metastatic colorectal cancer alive as long as the standard 28-day schedule, with far less toxicity.
