Step-up Approach Proves Effective in Treating Infected Necrotizing Pancreatitis

Real-life data from a single center experience show that the “step-up” approach for treating infected necrotizing pancreatitis is feasible, with an 80.5% success rate in resolving infections. The strategy had mild morbidity, a 19.5% mortality rate at 6 months, and led to long-term sequels in some patients (exocrine pancreatic insufficiency, diabetes, pancreatic fistula, parietal hernia). The approach demonstrates clinical-biological efficacy in a majority of cases, making it a promising option for managing the severe condition.